Hormone Therapy

Hormone Replacement

What is BHRT?

Biological hormone replacement therapy (BHRT) is aimed to restore physiological hormone levels in hormone deficient patients through an individualized approach. Based on a person’s exact hormone levels, BHRT uses customized doses of bioidentical hormones, which are chemically identical to the body’s naturally occurring hormones, to improve hormone insufficiencies.

What Are Pellets?

Fused pellets are a small cylindrical form of drug delivery that, when implanted under the skin by a physician, dissolve and release steady physiological doses of biological hormones over a period of several months.

Hormone replacement therapy by pellet implantation has been shown to be superior to other methods of hormone delivery because it supplies hormone blood levels that more closely resemble the body’s natural hormone cycle.

Fused pellets dissolve under the skin and therefore do not need to be removed. Pellets simply need to be replaced every 3-5 months for women or every 4-6 months for men, depending on patient-specific factors.

Why Use Pellets?

Using BHRT fused pellets eliminates the need for frequent administration of hormone therapy as is necessary with topical, vaginal, and oral therapy, thereby improving medication adherence and decreasing fluctuations in hormone levels.

Additionally, hormones delivered by pellet implantation have few adverse effects associated with blood clotting, blood pressure, lipid levels, blood glucose levels, and liver function.

Service Overview

Monitoring Pellet Therapy

Hormone levels will be drawn by the clinician and evaluated prior to therapy. This may include a FSH, estradiol, testosterone and free testosterone for women. Men need a PSA, sensitive estradiol (E2), serum free testosterone, total testosterone, SHBG, liver profile and blood count prior to starting therapy. Thyroid hormone levels may also be evaluated. Levels will be reevaluated during hormone therapy, usually prior to insertion of the next set of pellets, after 4-5 months. After the first year of therapy, hormones levels may be monitored less frequently. Women are advised to continue their monthly self-breast exam and obtain a mammogram and/or pap smear as advised by their gynecologist or primary care practitioner. Men must notify their primary care physician and obtain a digital rectal exam each year.


BHRT an acronym which stands for bio-identical hormone replacement therapy. Hormone replacement therapy has been a common practice to cope with aging for decades. BHRT can help those suffering from unbalanced hormones feel like themselves for the first time. Bio-identical hormones are derived from plant sources rather than animal sources or synthetic sources and are said to most closely replicate the molecular structure of human hormones.

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